diff --git a/src/Analyser/MutatingScope.php b/src/Analyser/MutatingScope.php
index 33e32539ff..ca9aded25d 100644
--- a/src/Analyser/MutatingScope.php
+++ b/src/Analyser/MutatingScope.php
@@ -105,6 +105,7 @@
 use PHPStan\Type\VoidType;
 use Throwable;
 use function abs;
+use function array_fill_keys;
 use function array_filter;
 use function array_key_exists;
 use function array_key_first;
@@ -3529,6 +3530,8 @@ public function filterBySpecifiedTypes(SpecifiedTypes $specifiedTypes): self
 			}
 		}
 
+		$scope = $scope->refreshDependentCallsAndFetches(array_keys($specifiedExpressions));
+
 		/** @var static */
 		return $scope->scopeFactory->create(
 			$scope->context,
@@ -3550,6 +3553,105 @@ public function filterBySpecifiedTypes(SpecifiedTypes $specifiedTypes): self
 		);
 	}
 
+	/**
+	 * When a receiver expression is narrowed, method calls and property fetches
+	 * on it that were narrowed by earlier control flow must be refined too, so
+	 * their remembered type combines with the one derived from the now-narrower
+	 * receiver.
+	 *
+	 * @param string[] $narrowedExprStrings
+	 */
+	private function refreshDependentCallsAndFetches(array $narrowedExprStrings): self
+	{
+		if (count($narrowedExprStrings) === 0) {
+			return $this;
+		}
+
+		$narrowedExprStringsMap = array_fill_keys($narrowedExprStrings, true);
+
+		$expressionTypes = $this->expressionTypes;
+		$nativeExpressionTypes = $this->nativeExpressionTypes;
+		$changed = false;
+
+		foreach ($this->expressionTypes as $exprString => $holder) {
+			$expr = $holder->getExpr();
+			if (
+				!$expr instanceof MethodCall
+				&& !$expr instanceof Expr\NullsafeMethodCall
+				&& !$expr instanceof PropertyFetch
+				&& !$expr instanceof Expr\NullsafePropertyFetch
+			) {
+				continue;
+			}
+
+			if (($expr instanceof MethodCall || $expr instanceof Expr\NullsafeMethodCall) && $expr->isFirstClassCallable()) {
+				continue;
+			}
+
+			if (!array_key_exists($this->getNodeKey($expr->var), $narrowedExprStringsMap)) {
+				continue;
+			}
+
+			$freshType = $this->resolveExprHandlerType($this, $expr);
+			$newType = TypeCombinator::intersect($holder->getType(), $freshType);
+			if (!$newType->equals($holder->getType())) {
+				$expressionTypes[$exprString] = new ExpressionTypeHolder($expr, $newType, $holder->getCertainty());
+				$changed = true;
+			}
+
+			if (!array_key_exists($exprString, $nativeExpressionTypes)) {
+				continue;
+			}
+
+			$nativeHolder = $nativeExpressionTypes[$exprString];
+			$freshNativeType = $this->resolveExprHandlerType($this->promoteNativeTypes(), $expr);
+			$newNativeType = TypeCombinator::intersect($nativeHolder->getType(), $freshNativeType);
+			if ($newNativeType->equals($nativeHolder->getType())) {
+				continue;
+			}
+
+			$nativeExpressionTypes[$exprString] = new ExpressionTypeHolder($expr, $newNativeType, $nativeHolder->getCertainty());
+			$changed = true;
+		}
+
+		if (!$changed) {
+			return $this;
+		}
+
+		return $this->scopeFactory->create(
+			$this->context,
+			$this->isDeclareStrictTypes(),
+			$this->getFunction(),
+			$this->getNamespace(),
+			$expressionTypes,
+			$nativeExpressionTypes,
+			$this->conditionalExpressions,
+			$this->inClosureBindScopeClasses,
+			$this->anonymousFunctionReflection,
+			$this->inFirstLevelStatement,
+			$this->currentlyAssignedExpressions,
+			$this->currentlyAllowedUndefinedExpressions,
+			$this->inFunctionCallsStack,
+			$this->afterExtractCall,
+			$this->parentScope,
+			$this->nativeTypesPromoted,
+		);
+	}
+
+	private function resolveExprHandlerType(self $scope, Expr $node): Type
+	{
+		/** @var ExprHandler<Expr> $exprHandler */
+		foreach ($scope->container->getServicesByTag(ExprHandler::EXTENSION_TAG) as $exprHandler) {
+			if (!$exprHandler->supports($node)) {
+				continue;
+			}
+
+			return $exprHandler->resolveType($scope, $node);
+		}
+
+		return new MixedType();
+	}
+
 	/**
 	 * @return array<string, ConditionalExpressionHolder[]>
 	 */
diff --git a/tests/PHPStan/Analyser/nsrt/bug-10050.php b/tests/PHPStan/Analyser/nsrt/bug-10050.php
new file mode 100644
index 0000000000..54b57cf265
--- /dev/null
+++ b/tests/PHPStan/Analyser/nsrt/bug-10050.php
@@ -0,0 +1,53 @@
+<?php // lint >= 8.0
+
+declare(strict_types = 1);
+
+namespace Bug10050;
+
+use function PHPStan\Testing\assertType;
+
+interface Value
+{
+	public function get(): int|string|null;
+}
+
+interface StringValue extends Value
+{
+	public function get(): string;
+}
+
+function testMethod(Value $v): void
+{
+	assertType('int|string|null', $v->get());
+	if ($v->get() === null) {
+		return;
+	}
+	assertType('int|string', $v->get());
+	if ($v instanceof StringValue) {
+		assertType('string', $v->get());
+	}
+	assertType('int|string', $v->get());
+}
+
+class A
+{
+	public int|null $p;
+}
+
+class B
+{
+	public string|null $p;
+}
+
+function testProperty(A|B $x): void
+{
+	assertType('int|string|null', $x->p);
+	if ($x->p === null) {
+		return;
+	}
+	assertType('int|string', $x->p);
+	if ($x instanceof A) {
+		assertType('int', $x->p);
+	}
+	assertType('int|string', $x->p);
+}